Institute halts COVID-19 clinical trial for hydroxychloroquine due to low enrollment - GeekWire
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Drug combination
Hydroxychloroquine and azithromycin was to have been the focus of a nationwide clinical trial enrolling 2,000 participants, but that study has been called off. (UW Medicine Photo)

The National Institute of Allergy and Infectious Diseases has shut down a clinical trial to see if a combination of hydroxychloroquine and azithromycin can prevent hospitalization and death due to COVID-19.

  • The trial, launched last month, aimed to enroll 2,000 outpatient participants nationwide — Another NIH clinical trial was halted as well.
  • Last week, UW Medicine said it was having a hard time with enrollment due to negative publicity about hydroxychloroquine. UW researchers are taking part in at least two other trials involving the drug, which has previously been approved for treating malaria and autoimmune diseases such as lupus and rheumatoid arthritis.
  • Also last week, the FDA revoked emergency use ization for hydroxychloroquine and a related drug, chloroquine. And the World Health Organization said it would no longer include hydroxychloroquine in its multi-drug trial to find an effective treatment for COVID-19. WHO said its decision was made based on preliminary results from its own trial and the British RECOVERY trial, suggesting that the drug did not reduce COVID-19 mortality.
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